Probiotics Combined With Chemotherapy for Patients With Advanced NSCLC

Phase 3 Unknown 180 enrolled Shanghai 10th People's Hospital Shanghai Chest Hospital · collab Shanghai Pulmonary Hospital, Shanghai, China · collab

RandomizedParallel-groupQuadruple-blindTreatment

Summary

Based on the theory of intestinal lung axis, the effect of new therapy on patients with advanced NSCLC was observed by adjusting the intestinal micro-ecology and combining existing platinum-based doublet chemotherapy.

Timeline

Start: 2019-02-21
Primary completion: 2024-03-01
Completion: 2024-03-01

Publications

Xia Q, Chen G, Ren Y, Zheng T, Shen C, Li M, Chen X, Zhai H, Li Z, Xu J, Gu A, Jin M, Fan L. Investigating efficacy of "microbiota modulation of the gut-lung Axis" combined with chemotherapy in patients with advanced NSCLC: study protocol for a multicenter, prospective, double blind, placebo controlled, randomized trial. BMC Cancer. 2021 Jun 22;21(1):721. doi: 10.1186/s12885-021-08448-6.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Bifico	Other / unclassified	420 mg	Oral

Indications

No indication recorded.