drugset

drugset / Trial / NCT03642665

Natural Versus Artificial Cycle for Frozen-Thawed Embryo Transfer

NCT03642665 ↗

Phase 4 Completed 554 enrolled Universitaire Ziekenhuizen KU Leuven GZA Ziekenhuizen Campus Sint-Augustinus · collab Imelda Hospital, Bonheiden · collab Jessa Hospital · collab

RandomizedParallel-groupOpen-labelTreatment

Summary

This study evaluates clinical pregnancy rates, obstetrical outcome parameters, costs and patient preferences in natural cycle versus artificial cycle frozen embryo transfers (FET).

Timeline

Start: 2018-09-25
Primary completion: 2024-11-01
Completion: 2024-11-01

Publications

Geysenbergh B, Debrock S, Lie Fong S, Vanhie A, Tomassetti C, Bafort C, Meeuwis L, Neyens S, Pelckmans S, Laenen A, Vriens J, De Loecker P, Dancet E, Peeraer K. Natural versus artificial cycle for endometrial preparation in ovulatory women undergoing frozen-thawed embryo transfer: a randomised controlled trial. Hum Reprod. 2026 Jun 19:deag095. doi: 10.1093/humrep/deag095. Online ahead of print.

Drugs

Evaluation	Drug	Modality	Dose	Route
Comparator	Progesterone	Other / unclassified	200 mg	Intravenous
Comparator	estradiol valerate	Unknown	6 mg	—
Comparator	estradiol valerate	Unknown	8 mg	—

Indications

No indication recorded.