drugset / Trial / NCT03645278

The PK/PD Study of SHR0532 Tablets in Healthy Subjects

NCT03645278

Phase 1 Unknown 50 enrolled Jiangsu HengRui Medicine Co., Ltd.
RandomizedParallel-groupQuadruple-blindTreatment

Summary

In the last four decades, several classes of diuretics have been the first line option for the therapy of widespread hypertension. However, all the classes of diuretics cause alteration of potassium homeostasis. The primary objective of this study is to assess the safety and tolerability of SHR0532 tablets in healthy subjects. In addition, this study will provide information on Pharmacokinetics and Pharmacodynamics of SHR0532 tablets in healthy subjects.

Timeline

Start
2018-08-24
Primary completion
2018-12-15
Completion
2019-04-30

Drugs

EvaluationDrugModalityDoseRoute
Subject SHR0532 Unknown Oral

Indications