drugset / Trial / NCT03647514

Abraxane Combined With Xeloda as Neo-Adjuvant Chemotherapy in Early Breast Cancer

NCT03647514

Unknown 50 enrolled Zhejiang Cancer Hospital
NaSingle-groupOpen-labelTreatment

Summary

Some studies have demonstrated the efficacy of Abraxane in treating breast cancer in both adjuvant and metastatic settings. Few data is available on Abraxane in neoadjuvant treatment for breast cancer. The aim of this project is to evaluate tailored primary systemic therapy with weekly Abraxane (125mg/m2) Combined With Q3week Xeloda (1250mg/m2) in early operable (stage of T2-4N0-3M0) breast cancer. This study will be an open label non randomized, single arm, single center study.

Timeline

Start
2018-12-01
Primary completion
2020-09-30
Completion
2020-09-30

Drugs

EvaluationDrugModalityDoseRoute
Subject Capecitabine Small molecule 1250 mg/m2
Subject Paclitaxel Small molecule 125 mg/m2

Indications