GDNF in ideopathicParkinsons Disease

Summary

A Placebo Controlled Randomised Trial of GDNF vs placebo The study will require patients to undergo surgery to implant microcatheters precisely into the brain. Patients will then attend clinic on a 2 weekly basis for infusions of a nerve growth factor called GDNF or placebo. Specific tests will also be carried out at regular intervals to assess your symptoms. All participants will undergo radio-isotope brain imaging at the beginning and end of the study. Periodically patients will also be required to undergo an MRI scan to assess the delivery of the study drug or placebo.

Timeline

Start

2012-10-25

Primary completion

2015-03-13

Completion

2016-04-01

Drugs

Indications