drugset / Trial / NCT03653702

Radiation-Free Technique for Evaluating Renal Scarring (RAFTERS)

NCT03653702

Phase 1 Unknown 70 enrolled Boston Children's Hospital
NaSingle-groupOpen-labelDiagnostic

Summary

In this research study the investigators want to study a safe, radiation-free technique known as contrast-enhanced ultrasound that may improve the ability to diagnose or evaluate renal scarring compared to regular ultrasound. This technique requires injection into a vein of a small amount of contrast material called Lumason. Contrast material is a type of dye that helps the investigators image the structures in the body more clearly. If this technique is successful, the need for DMSA studies may be avoided to diagnose or evaluate kidney scarring. DMSA is a more expensive test, causes radiation exposure, may require sedation and/or injection of contrast agents with the potential to cause allergic reactions.

Timeline

Start
2023-10-01
Primary completion
2024-04
Completion
2024-06

Drugs

EvaluationDrugModalityDoseRoute
Subject Lumason Diagnostic / imaging agent 0.03 unknown Intravenous

Indications