drugset / Trial / NCT03656120
A Study of Thienorphine Hydrochloride Tablets in Relapse Prevention Treatment of Opioid Dependence
Phase 2
Unknown
180 enrolled
Wei Hao
Beijing ziduhongye technology development co. LTD · collabInstitute of Pharmacology and Toxicology, Academy of Military Medical Science · collabShanghai Mental Health Center · collabWest China Hospital · collabWuhan Mental Health Centre · collab
RandomizedParallel-groupTriple-blindTreatment
Summary
Opioid addiction is common worldwide. Thienorphine hydrochloride is a newly partial opioid receptor agonist drugs. It's affinity with opioid receptors was much higher than opioids, which could effectively prevents opioid dependence by stop opioids competition for opioid receptors and causing opioid dependence. The aim of this research was to determine whether thienorphine hydrochloride would reduce opioid use and better preventing relapse among opioid addicts.
Timeline
- Start
- 2018-08-31
- Primary completion
- 2019-08-31
- Completion
- 2019-12-31
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Thienorphine | Unknown | 0.2 mg | — |
| Subject | Thienorphine | Unknown | 0.5 mg | — |