drugset / Trial / NCT03656926

Efficacy + Safety of Liposome Cyclosporine A to Treat Bronchiolitis Obliterans Post Double Lung Transplant (BOSTON-2)

NCT03656926

Phase 3 Completed 169 enrolled Zambon SpA
RandomizedParallel-groupSingle-blindTreatment

Summary

The objective of this trial was to assess the efficacy and safety of aerosolized liposomal cyclosporine A (L-CsA) as add-on therapy to standard of care (SoC) as compared to SoC alone in double lung transplant (DLT) recipients with chronic lung allograft dysfunction (CLAD)-bronchiolitis obliterans syndrome (BOS).

Timeline

Start
2019-03-26
Primary completion
2024-03-12
Completion
2024-03-12

Drugs

EvaluationDrugModalityDoseRoute
Subject Cyclosporine Peptide 10 mg Inhaled