drugset / Trial / NCT03657537

Effects of Ketone Bodies on Cognition in Type 2 Diabetes

NCT03657537 ↗

RandomizedCrossoverDouble-blindBasic science

Summary

Diabetes negatively affects cognition and increases the risk of developing overt dementia. Decreased cerebral glucose metabolism may be contributing to this effect, thus providing a glucose substitute using ketone bodies might improve neuronal function. In this study the investigators propose to provide quantitative results on cognitive performance during acute hyperketonemia in patients with type 2 diabetes.

Timeline

Start
2018-09-17
Primary completion
2019-02-14
Completion
2019-02-14

Drugs

EvaluationDrugModalityDoseRoute
Subject β-hydroxybutyrate Unknown — Intravenous