A Clinical Study to Test Efficacy and Safety of Repeat Doses of CNTX-4975-05 in Patients With Osteoarthritis Knee Pain

Summary

This is a randomized, double-blind, placebo-controlled, 2-injection, 52-week study to evaluate the efficacy and safety of intra-articular injections of CNTX-4975-05 in subjects with chronic, moderate-to-severe osteoarthritis knee pain.

Timeline

Start

2018-09-09

Primary completion

2020-06-11

Completion

2020-06-11

Outcome

Missed primary endpoint

registry analysis (superiority test); Placebo vs CNTX-4975-05; p = 0.0833; Mean Difference (Final Values) -2.07 (95% CI -4.42 to 0.27) NCT03660943 ↗

Drugs

Indications