drugset / Trial / NCT03666195

The Anti-microbial Effect of Titanium Dioxide Nano Particles in Complete Dentures Made for Edentulous Patients

NCT03666195

Unknown 20 enrolled Cairo University
RandomizedParallel-groupDouble-blindPrevention

Summary

Although cleaning dentures by immersion in chemical denture cleaning solutions is effective in reducing the number of bacteria, a large number remains adhering to the denture surface. Thus, the mechanical cleansing of dentures is imperative to remove adherent microbes, and prevent diseases. This is not always easy to achieve, due to un-compliant patients, or patients with diminished manual dexterity (e.g. Mani phalanx dysfunction or Rheumatoid Arthritis) that often require assistance in cleaning their dentures, which may not always be available. Therefore, the modification of denture base materials to provide them with antibacterial properties to control oral biofilm formation, and producing dentures that can be cleaned by simply rinsing in water would prove to be valuable in oral hygienic management in complete denture-wearing patients.

Timeline

Start
2018-10-15
Primary completion
2018-12-15
Completion
2019-01-15

Drugs

EvaluationDrugModalityDoseRoute
Subject Titanium Dioxide Nanoparticles Other / unclassified 5 %