drugset / Trial / NCT03669601
AZD6738 & Gemcitabine as Combination Therapy
RandomizedParallel-groupOpen-labelTreatment
Summary
A dose escalation trial to assess the safety of AZD6738 in combination with gemcitabine in participants with advanced solid tumours.
Timeline
- Start
- 2019-10-15
- Primary completion
- 2023-09-30
- Completion
- 2024-09-30
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Ceralasertib | Small molecule | 40 mg | Oral |
| Subject | Ceralasertib | Small molecule | 120 mg | Oral |
| Subject | Gemcitabine | Small molecule | 500 mg/m2 | Intravenous |
| Subject | Gemcitabine | Small molecule | 1000 mg/m2 | Intravenous |