Study of the Fecal Microbiome in Patients With Parkinson's Disease

Phase 1 Completed 15 enrolled The University of Texas Health Science Center, Houston Kelsey Research Foundation · collab

RandomizedParallel-groupSingle-blindTreatment

Summary

The purpose of this study is to characterize the intestinal microbiome in subjects with Parkinson's disease and to determine safety and trends in improvements in diversity of colonic microbiome following administration of lyophilized PRIM-DJ2727

Timeline

Start: 2019-05-15
Primary completion: 2022-10-09
Completion: 2022-10-12

Publications

DuPont HL, Suescun J, Jiang ZD, Brown EL, Essigmann HT, Alexander AS, DuPont AW, Iqbal T, Utay NS, Newmark M, Schiess MC. Fecal microbiota transplantation in Parkinson's disease-A randomized repeat-dose, placebo-controlled clinical pilot study. Front Neurol. 2023 Mar 2;14:1104759. doi: 10.3389/fneur.2023.1104759. eCollection 2023.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	PRIM-DJ2727	Other / unclassified	60 g	Oral

Study of the Fecal Microbiome in Patients With Parkinson's Disease

Summary

Timeline

Publications

Drugs

Indications