drugset / Trial / NCT03680378
Lung Pharmacokinetics (PK) in Epithelial Lining Fluid (ELF)
NaSingle-groupOpen-labelOther
Summary
The primary objective of this study is to measure and compare the concentration of AAI101 and cefepime in bronchial epithelial lining fluid (ELF) and plasma following administration of cefepime/AAI101 combination in healthy subjects.
Timeline
- Start
- 2017-07-01
- Primary completion
- 2019-04-30
- Completion
- 2019-04-30
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Cefepime | Small molecule | 2 g | Intravenous |
| Subject | enmetazobactam | Small molecule | 1 g | Intravenous |
Indications
No indication recorded.