drugset / Trial / NCT03682367

Perioperative Analgesia Using Gabapentin in Head and Neck Cancer Surgery

NCT03682367

Phase 3 Terminated 8 enrolled University of California, Davis
RandomizedParallel-groupTriple-blindSupportive care

Summary

Patients undergoing head and neck cancer surgery often have a lot of pain after surgery, which can lead to a need for a lot of narcotic pain medication. These medications can have many side effects that can make recovery more difficult including nausea, vomiting, dizziness, being overly sleepy, itchiness, inability to urinate, confusion, inability to have a bowel movement, longer time before being able to start walking. These side effects can make the hospital stay longer. The use of gabapentin, which is a non narcotic pain medication that focuses on nerve pain, has been used in smaller head and neck surgeries including removal of tonsils, sinus surgery, thyroid surgery. Studies in patients needing orthopedic or OB/Gyn surgery have shown improved pain control with gabapentin. Potential benefits to future patients include improved pain control, less narcotic associated side effects and faster functional recovery.

Timeline

Start
2018-12-01
Primary completion
2020-04-01
Completion
2020-04-06

Drugs

EvaluationDrugModalityDoseRoute
Subject Gabapentin Small molecule

Indications