A Study of Seltorexant (JNJ-42847922) After Single-Dose Administration in Healthy Participants

Summary

The purpose of this study is to compare the rate and extent of absorption (relative bioavailability) of seltorexant Phase 3 test formulation(s) relative to a reference Phase 2b tablet formulation dosed in the evening under fasted and semi-fasted conditions (3 hours after meal); to assess the effect of type and timing of the meal on the rate and extent of absorption of seltorexant Phase 3 tablet formulation (low dose and high dose strength) in healthy male and female participants; and to assess the pharmacokinetic of single-dose administration of low dose and high dose of seltorexant in healthy male and female participants 3 hours after meal.

Timeline

Start

2018-10-01

Primary completion

2019-08-23

Completion

2019-08-23

Drugs

Indications

No indication recorded.