drugset / Trial / NCT03687515

Efficacy and Safety of Budesonide Inhalation Suspension for the Treatment of Chronic Rhinosinusitis With Polyposis.

NCT03687515

Phase 3 Completed 91 enrolled Beijing Tongren Hospital
RandomizedParallel-groupOpen-labelTreatment

Summary

Topical and systemic steroids constitute the first choice in medical treatment for nasal polyps. This study aimed to evaluate the efficacy and safety of a short course of budesonide inhalation suspension via transnasal nebulization in the preoperative management of chronic rhinosinusitis with nasal polyposis. The second aim was to compare budesonide inhalation suspension with budesonide aqueous nasal spray and oral prednisone in nasal polyp treatment.

Timeline

Start
2015-01-01
Primary completion
2016-12-03
Completion
2017-11-30

Drugs

EvaluationDrugModalityDoseRoute
Comparator Budesonide Small molecule 256 ug Intranasal
Comparator Budesonide Small molecule 1 mg Intranasal
Comparator Prednisone Other / unclassified 24 mg Oral