drugset / Trial / NCT03687515
Efficacy and Safety of Budesonide Inhalation Suspension for the Treatment of Chronic Rhinosinusitis With Polyposis.
RandomizedParallel-groupOpen-labelTreatment
Summary
Topical and systemic steroids constitute the first choice in medical treatment for nasal polyps. This study aimed to evaluate the efficacy and safety of a short course of budesonide inhalation suspension via transnasal nebulization in the preoperative management of chronic rhinosinusitis with nasal polyposis. The second aim was to compare budesonide inhalation suspension with budesonide aqueous nasal spray and oral prednisone in nasal polyp treatment.
Timeline
- Start
- 2015-01-01
- Primary completion
- 2016-12-03
- Completion
- 2017-11-30
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Budesonide | Small molecule | 256 ug | Intranasal |
| Comparator | Budesonide | Small molecule | 1 mg | Intranasal |
| Comparator | Prednisone | Other / unclassified | 24 mg | Oral |