drugset / Trial / NCT03701451

Demethylated Drug in the Treatment of Nasopharyngeal Carcinoma

NCT03701451

NaSingle-groupOpen-labelTreatment

Summary

The study is to observe the efficacy and toxicity of demethylating drug decitabine and cisplatin induced chemotherapy for 3 cycles followed by concurrent chemoradiotherapy in the treatment of regionally advanced nasopharyngeal carcinoma,followed up for 2 years, observing the 2-year survival rate and variation of degrees of methylation before and after treatment,providing clinical basis for the clinical study of stage II-III.

Timeline

Start
2018-02-28
Primary completion
2020-12-01
Completion
2020-12-01

Drugs

EvaluationDrugModalityDoseRoute
Subject Decitabine Small molecule 7 mg/m2