drugset / Trial / NCT03702140

Examination How the Administration Period of Teriparatide Affects Bone Metabolism and Bone Mineral Density Prior to Denosumab Therapy

NCT03702140

Phase 2 Unknown 90 enrolled Shinshu University
RandomizedParallel-groupSingle-blindTreatment

Summary

The aim of this study is to examine the efficacy and adverse events in the following 3 groups in osteoporosis patients: 1. The administration period of teriparatide is less than 6 months and thereafter, denosumab for 24 months. 2. The administration period of teriparatide is from 6 to 12 months and thereafter, denosumab for 24 months. 3. The administration period of teriparatide is more than 12 months and thereafter, denosumab for 24 months.

Timeline

Start
2018-10-09
Primary completion
2023-10-08
Completion
2025-10-08

Drugs

EvaluationDrugModalityDoseRoute
Comparator Teriparatide Protein / enzyme biologic

Indications