drugset / Trial / NCT03706261

Alzheimer's PET Imaging in Racially/Ethnically Diverse Adults

NCT03706261

NaSingle-groupOpen-labelBasic science

Summary

The study employs tau positron emission tomography (PET) imaging in a well-characterized multi-racial/ethnic cohort to examine the extent to which tau pathology is associated with cognition, differences in tau pathology across racial/ethnic groups, and the relationship between MRI markers of small-vessel cerebrovascular disease and tau pathology. The study also investigates amyloid-dependent tau spreading.

Timeline

Start
2019-03-22
Primary completion
2023-07-14
Completion
2023-07-14

Drugs

EvaluationDrugModalityDoseRoute
Subject 18F-Florbetaben Diagnostic / imaging agent 299.7 mbq Intravenous
Subject 18F-MK-6240 Diagnostic / imaging agent 185 mbq

Indications