drugset / Trial / NCT03706781
A Novel Mouthwash Formulation CTP/BNZ With Mucus Adhesive Polymer
RandomizedCrossoverOpen-labelOther
Summary
The purpose of the study is to evaluate the local tolerability and the systemic availability of benzydamine, if any, after single and multiple dose treatment with the test formulation containing cetylpyridinium chloride 0.05% + benzydamine hydrochloride 0.15% + mucoadhesive polymer and with the reference formulation Tantum Verde Bocca containing cetylpyridinium chloride 0.05% + benzydamine hydrochloride 0.15% to healthy subjects , under fasting conditions, in two consecutive study periods.
Timeline
- Start
- 2017-11-14
- Primary completion
- 2017-12-18
- Completion
- 2018-03-30
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Benzydamine | Unknown | 0.15 % | — |
| Subject | Cetylpyridinium | Small molecule | 0.05 % | — |
Indications
No indication recorded.