drugset / Trial / NCT03708887
The Effect of Omega-3 FA on Glucose and Lipid Homeostasis Disorders in Obese/Diabetic Patients
RandomizedParallel-groupQuadruple-blindTreatment
Summary
A double-blind and placebo-controlled study is conducted in the current human study. The purpose of this study is to investigate the effects of n-3 PUFA intervention on glucose and lipid homeostasis in Chinese diabetic/obese patients.
Timeline
- Start
- 2020-10-10
- Primary completion
- 2022-01-02
- Completion
- 2022-02-28
Publications
- Zhuang P, Liu X, Jia W, Zheng W, Wan X, Chen W, Gu J, Li Y, Lan X, Li H, Tong W, Wu Y, Wu X, Ao Y, Ye H, Wu F, Zhu L, Zhang L, Li Y, Meng D, Tian Y, Wang A, Wu S, Zhu F, Zhang Y, Shi H, Yu X, Zhang F, Zhang Y, Jiao J. Marine n-3 fatty acid treatment for carotid plaques in patients with type 2 diabetes. Cardiovasc Diabetol. 2026 Jan 20;25(1):52. doi: 10.1186/s12933-026-03082-7.
- Zhuang P, Wu Y, Yao J, Liu X, Liu H, Wan X, Jia W, Wang T, Zhang Y, Jiao J. Marine n-3 polyunsaturated fatty acids slow sleep impairment progression by regulating central circadian rhythms in type 2 diabetes. Cell Rep Med. 2025 May 20;6(5):102128. doi: 10.1016/j.xcrm.2025.102128. Epub 2025 May 9.
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Omega-3 fatty acids | Unknown | 1.5 g | Oral |
| Subject | Omega-3 fatty acids | Unknown | 3 g | Oral |