drugset / Trial / NCT03712280

MNK6106 for Liver Disease (Hepatic Cirrhosis) That in the Past Has Affected the Brain (Hepatic Encephalopathy)

NCT03712280

Phase 2 Completed 50 enrolled Mallinckrodt
RandomizedParallel-groupOpen-labelTreatment

Summary

The main reason for this study is to see how the study drug interacts with the body. It will compare different doses of the study drug with a drug already in use. Participants will be adults with liver disease that has affected the brain in the past.

Timeline

Start
2018-12-01
Primary completion
2020-07-14
Completion
2020-07-14

Drugs

EvaluationDrugModalityDoseRoute
Subject MNK6106 Unknown 2 g Oral
Subject MNK6106 Unknown 4 g Oral
Comparator Rifaximin Other / unclassified 550 mg Oral