drugset / Trial / NCT03722875

SHR-1210 Plus Apatinib in Patients With Hepatocellular Carcinoma After Surgery

NCT03722875

Unknown 45 enrolled Shanghai Zhongshan Hospital
NaSingle-groupOpen-labelTreatment

Summary

SHR-1210 is a humanized anti-PD1 Immunoglobulin G4 (IgG4) monoclonal antibody. This is an open- label,single center ,non-randomized ,Single Arm Exploratory Study . This clinical study is an investigator-initiatedclini-cal trial(IIT ).The objective of this study is to evaluate the efficacy and safety of adjuvant therapy with anti-PD-1 antibody SHR-1210 and apatinib in patients with Barcelona Clinic Liver Cancer (BCLC) B\&C stage hepatocellular carcinoma after surgery.

Timeline

Start
2018-12-01
Primary completion
2019-03-01
Completion
2020-03-01

Drugs

EvaluationDrugModalityDoseRoute
Subject Camrelizumab Monoclonal antibody 200 mg Intravenous
Subject Rivoceranib Small molecule 250 mg