drugset / Trial / NCT03724851

Vactosertib in Combination with Pembrolizumab in Metastatic Colorectal or Gastric Cancer

NCT03724851

Phase 1/2 Completed 120 enrolled MedPacto, Inc. Merck Sharp & Dohme LLC · collab
Non-randomizedParallel-groupOpen-labelTreatment

Summary

This is an open-label, multicenter study to assess the safety, tolerability, pharmacokinetics, and antitumor activity of vactosertib in combination with pembrolizumab in patients with metastatic or locally advanced colorectal or gastric/gastroesophageal junction adenocarcinoma

Timeline

Start
2018-12-20
Primary completion
2024-05-07
Completion
2024-05-07

Drugs

EvaluationDrugModalityDoseRoute
Subject Vactosertib Small molecule 200 mg Oral
Subject Vactosertib Small molecule 300 mg Oral