drugset / Trial / NCT03733002
Efficacy and Safety of AngongNiuhuang Pill for the Treatment of Patients With Acute Ischemic Stroke.
Phase 3
Unknown
100 enrolled
Peking Union Medical College Hospital
Affiliated Hospital of Chengde Medical University · collabCangzhou Central Hospital · collabChina-Japan Friendship Hospital · collabThe Second Hospital of Hebei Medical University · collab
RandomizedParallel-groupDouble-blindTreatment
Summary
AngongNiuhuang pill has obvious effects on the cardiovascular and cerebrovascular, especially the cerebral vessels. Pharmacological experiments confirmed that AngongNiuhuang pill can protect blood-brain barrier, reduce capillary permeability, improve the tolerance of cerebral ischemia and hypoxia, improve oxidative stress injury, thus protecting brain tissue. Clinical studies have also confirmed that AngongNiuhuang pill can increase the GCS score, reduce coma, improve nerve function defect and promote nerve function recovery. The primary purpose of this trial was to evaluate the effect of AngongNiuhuang pill and placebo on the improvement of life function in patients with ischemic stroke at 90 days in acute phase.
Timeline
- Start
- 2018-12-01
- Primary completion
- 2019-12-30
- Completion
- 2019-12-30
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | AngongNiuhuang pill | Unknown | 1 unknown | — |