drugset / Trial / NCT03735095
Endobronchial Ultrasound Guided Interstitial Photodynamic Therapy in Treating Patients With Locally Advanced Lung Cancer
Phase 1/2
Completed
19 enrolled
Roswell Park Cancer Institute
National Cancer Institute (NCI) · collabPinnacle Biologics Inc. · collabSimphotek Inc. · collab
NaSingle-groupOpen-labelTreatment
Summary
This Phase I/Il studies the side effects of endobronchial ultrasound guided interstitial photodynamic therapy work in treating patients with lung cancer that has spread to nearby tissues or lymph nodes. Photodynamic therapy consists of injecting a light sensitive drug called a photosensitizer, such as porfimer sodium, into the vein, waiting for it to accumulate in the tumor, and then activating it with a red laser light. Giving photodynamic therapy with Porfimer sodium may reduce the tumor size in patients with lung cancer.
Timeline
- Start
- 2020-02-12
- Primary completion
- 2024-07-26
- Completion
- 2024-07-26
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | porfimer sodium | Small molecule | 2 mg/kg | Intravenous |