drugset / Trial / NCT03735758

Quality of Life in Patients With Non-adipocyte Soft Tissue Sarcoma Under Palliative Chemotherapy or Pazopanib

NCT03735758

Phase 4 Terminated 11 enrolled GWT-TUD GmbH
RandomizedParallel-groupOpen-labelTreatment

Summary

Finding the balance between toxicity and benefit should be the major goal when negotiating about the therapeutic regimen. This becomes nowadays even more important, since there are emerging options in the field of sarcoma therapy. Especially in the palliative treatment of sarcoma patients, knowing that na single drug can provide an overall survival benefit, physicians have to incorporate the patient's preferences and goals in life when consulting them. The study will allow patients with several types of soff tissue sarcoma to be included. After progression under current therapy, the patient will be randomized in a 1:1 fashion and allocated to either pazopanib or investigator's choice. Quality of life (QoL) and other secondary outcome measures will be recorded continuously. The aim of the study is to assess patient reported outcomes (PROs), which should be the primary aim when treating these patients.

Timeline

Start
2018-11-02
Primary completion
2020-10-06
Completion
2020-10-06

Drugs

EvaluationDrugModalityDoseRoute
Subject Pazopanib Small molecule 800 mg Oral

Indications