Recombinant FSH Investigation in the Treatment of Infertility With Assisted Reproductive Technology (ART) (RITA-2)

Summary

This trial investigates the effects of FE 999049 compared to placebo.

Timeline

Start

2018-10-29

Primary completion

2020-12-21

Completion

2020-12-21

Outcome

Met primary endpoint

registry analysis (other test); FE 999049 (Follitropin Delta) vs Placebo; p <0.001; Treatment difference 43.3 (95% CI 36.5 to 47.6); Fisher Exact NCT03738618 ↗

Publications

• Scheiber MD, Doody KJ, Foster ED, Grover SA, Heiser PW; RITA-1 and RITA-2 (Recombinant FSH Investigation in the Treatment of Infertility with ART) trial groups. Ovarian stimulation with follitropin delta is safe and effective: results from the RITA randomized, double-blind, placebo-controlled trials. Fertil Steril. 2026 Jan;125(1):54-63. doi: 10.1016/j.fertnstert.2025.07.032. Epub 2025 Jul 24.

Drugs

Indications