drugset / Trial / NCT03746288

To Evaluate the Efficacy and Safety of CAN008 Combined With Re-irradiation (rRT) for Treating Patients With Recurrent Glioblastoma (GBM)

NCT03746288 ↗

Phase 2 Unknown 60 enrolled CANbridge Life Sciences Ltd.
RandomizedParallel-groupOpen-labelTreatment

Summary

This is a multicenter, randomized, controlled study, aiming to evaluate the efficacy and safety of CAN008 administered once-weekly with rRT for treating first tumor recurrence in patients with GBM.

Timeline

Start
2018-11-20
Primary completion
2021-07-01
Completion
2021-12-31

Outcome

Met primary endpoint

release “Treatment with CAN008 significantly improved progression-free survival in the Phase 2 clinical trial of recurrent glioblastoma conducted by Apogenix in Germany” canbridgepharma.com ↗

Drugs

EvaluationDrugModalityDoseRoute
Subject Asunercept Protein / enzyme biologic 400 mg Intravenous

Indications