Phase Ib/IIa Studies of Chlorogenic Acid for Injection for Safety and Efficacy of Advanced Lung Cancer

Phase 1/2 Unknown 144 enrolled Sichuan J.Z. Bio-chemical Science and Technology Development Co., Ltd Cancer Institute and Hospital, Chinese Academy of Medical Sciences · collab

NaSingle-groupOpen-labelTreatment

Summary

This Ib / IIa clinical trial program focuses on the small cell lung cancer (SCLC), Squamous non-small cell lung cancer (NSCLC) and adeniform NSCLC in order to start a better development on the broad-spectrum value of chlorogenic acid： Determine the Disease control rate（DCR）of phase Ib/IIa of Chlorogenic acid for injection in the advanced Lung Cancer Patients.

Timeline

Start: 2018-07-17
Primary completion: 2020-10-30
Completion: 2021-04-30

Publications

Zhu H, Chen J, Dong X, Qin X, Li Z. Influence of dihydrocaffeic acid and quinic acid on lung metabolism and function: Implications for dietary interventions. Biochem Biophys Res Commun. 2025 Sep 1;777:152274. doi: 10.1016/j.bbrc.2025.152274. Epub 2025 Jun 28.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Chlorogenic acid	Small molecule	—	—

Phase Ib/IIa Studies of Chlorogenic Acid for Injection for Safety and Efficacy of Advanced Lung Cancer

Summary

Timeline

Publications

Drugs

Indications