drugset / Trial / NCT03759288
An Active and Placebo-Controlled Study of Brazikumab in Participants With Moderately to Severely Active Crohn's Disease
RandomizedParallel-groupTriple-blindTreatment
Summary
This study seeks to evaluate the safety and efficacy of brazikumab versus placebo (Stage I) and versus an active comparator (Stage 2) in participants with moderately to severely active CD and will include assessments of clinical response as demonstrated by improvement of symptoms and colonic mucosal appearance as observed on endoscopy
Timeline
- Start
- 2018-12-07
- Primary completion
- 2023-10-18
- Completion
- 2023-10-18
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Adalimumab | Monoclonal antibody | — | Subcutaneous |
| Subject | Brazikumab | Unknown | — | Intravenous |