drugset / Trial / NCT03761407
A Clinical Study in Healthy Subjects Which Aims to Investigate the Safety, the Tolerability and the Effects of GRT0151Y and How the Compound is Taken up and Excreted From the Body
RandomizedCrossoverQuadruple-blindTreatment
Summary
The aim of this clinical study in healthy participants is to investigate the safety and tolerability of GRT0151Y after multiple oral intake of different increasing doses and to evaluate the pharmacological effects (action of the compound) by means of pupillometry (measuring the pupil size of the eye) and Cold Presser Test (measuring the pain when immersing the hand in 2 degree Celsius cold water). An additional aim of the study is to investigate the pharmacokinetics of GRT0151Y (how it is taken up into the body and how it is excreted from the body)."
Timeline
- Start
- 2004-12-30
- Primary completion
- 2005-07-26
- Completion
- 2005-07-26
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | GRT0151Y | Unknown | 100 mg | Oral |
| Subject | GRT0151Y | Unknown | 125 mg | Oral |
| Subject | GRT0151Y | Unknown | 150 mg | Oral |
| Subject | GRT0151Y | Unknown | 225 mg | Oral |
Indications
No indication recorded.