drugset / Trial / NCT03765931
Comparative Efficacy of Single-dose Doxycycline Versus Standard 5- Day Amoxicillin Treatment
RandomizedParallel-groupOpen-labelTreatment
Summary
Abstract: Background The current practice in Senegal is to use broad-spectrum antibiotics including amoxicillin and/or cotrimoxazole in case of non-malarial fevers. First-line treatment with doxycycline has cured such patients. The investgators aimed to determine the efficacy of a single dose of doxycycline compared to a 5-day amoxicillin course for the treatment of fever.
Timeline
- Start
- 2016-07
- Primary completion
- 2017-01
- Completion
- 2017-10
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Amoxicillin | Other / unclassified | 20 mg/kg | — |
| Comparator | Amoxicillin | Other / unclassified | 500 mg | — |
| Comparator | Doxycycline | Small molecule | 30 mg/kg | — |
| Comparator | Doxycycline | Small molecule | 100 mg | — |
Indications
No indication recorded.