drugset / Trial / NCT03770260

Ixazomib and Pevonedistat in Treating Patients With Multiple Myeloma That Has Come Back or Does Not Respond to Treatment

NCT03770260

Phase 1 Completed 8 enrolled National Cancer Institute (NCI)
NaSingle-groupOpen-labelTreatment

Summary

This phase Ib trial studies side effects and best dose of pevonedistat when given together with ixazomib in treating patients with multiple myeloma that has come back or does not respond to treatment. Pevonedistat and ixazomib may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth.

Timeline

Start
2020-02-10
Primary completion
2022-09-12
Completion
2023-07-06

Drugs

EvaluationDrugModalityDoseRoute
Subject Ixazomib Unknown Oral
Subject Pevonedistat Small molecule Intravenous

Indications