drugset / Trial / NCT03771586

A Study to Assess the Electrophysiology, Safety, Tolerability, and Pharmacokinetics of SAGE-718 Using a Ketamine Challenge in Healthy Subjects

NCT03771586

Phase 1 Completed 22 enrolled Supernus Pharmaceuticals, Inc.
RandomizedCrossoverQuadruple-blindBasic science

Summary

This study is a phase 1, double-blind, placebo-controlled crossover study of single, oral dose of SAGE-718 using a ketamine challenge, to evaluate the electrophysiology, safety, tolerability, and pharmacokinetics in healthy subjects

Timeline

Start
2018-09-24
Primary completion
2018-12-17
Completion
2019-01-02

Drugs

EvaluationDrugModalityDoseRoute
Subject Dalzanemdor Small molecule Oral
Background Ketamine Small molecule

Indications

No indication recorded.