drugset / Trial / NCT03776071

A Trial of Enzastaurin Plus Temozolomide During and Following Radiation Therapy in Patients With Newly Diagnosed Glioblastoma With or Without the Novel Genomic Biomarker, DGM1

NCT03776071

Phase 3 Completed 260 enrolled Denovo Biopharma LLC
RandomizedParallel-groupTriple-blindTreatment

Summary

This study will be conducted as a randomized, double-blind, placebo-controlled, multi-center Phase 3 study. Approximately 300 subjects with newly diagnosed glioblastoma who meet all eligibility criteria will be enrolled.

Timeline

Start
2020-12-16
Primary completion
2024-02-29
Completion
2024-02-29

Drugs

EvaluationDrugModalityDoseRoute
Comparator enzastaurin Small molecule
Comparator Temozolomide Small molecule

Indications