drugset / Trial / NCT03777215
Angiotensin-(1-7) and Energy Expenditure in Human Obesity
RandomizedParallel-groupDouble-blindOther
Summary
The objective of this study is to better define the role of the hormone angiotensin-(1-7) in energy balance. We will test the overall hypothesis that angiotensin-(1-7) increases resting energy expenditure and promotes markers of heat production (thermogenesis) in white adipose tissue in human obesity.
Timeline
- Start
- 2019-09-26
- Primary completion
- 2026-12
- Completion
- 2026-12
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | talfirastide | Peptide | 2 unknown | Intravenous |
| Subject | talfirastide | Peptide | 4 unknown | Intravenous |
| Subject | talfirastide | Peptide | 8 unknown | Intravenous |