drugset / Trial / NCT03777462

Borderline Resectable Pancreatic Cancer Neoadjuvant Chemoradiotherapy Clinicaltrial-1

NCT03777462 ↗

Phase 2 Unknown 150 enrolled Changhai Hospital
RandomizedParallel-groupOpen-labelTreatment

Summary

This study is to investigate whether neoadjuvant chemotherapy plus SBRT results in better outcomes compared with neoadjuvant chemotherapy alone and also compare the efficacy of gemcitabine plus nab-paclitaxel with SBRT and S-1 plus nab-paclitaxel with SBRT.

Timeline

Start
2019-04-01
Primary completion
2023-12-31
Completion
2023-12-31

Drugs

EvaluationDrugModalityDoseRoute
Comparator Gemcitabine Small molecule 1000 mg/m2 Intravenous
Subject S-1 Small molecule 80 mg/m2 Oral
Comparator Nab-paclitaxel Small molecule 125 mg/m2 Intravenous