drugset / Trial / NCT03781765

Stimulant vs. Non-stimulant Treatments and Reward Processing in Drug-naive Youth at SUD Risk

NCT03781765

RandomizedSingle-groupOpen-labelBasic science

Summary

The study team will examine the effects of FDA approved stimulant and non-stimulant medications for ADHD, among youth with ADHD and with and without Oppositional Defiant Disorder (ODD) or Conduct Disorder (CD), on reward systems of the brain using fMRI.

Timeline

Start
2019-06-04
Primary completion
2025-09-25
Completion
2025-09-25

Drugs

EvaluationDrugModalityDoseRoute
Comparator Atomoxetine Other / unclassified 1 mg/kg
Comparator Methylphenidate Small molecule 1 mg/kg