drugset / Trial / NCT03784963

Efficacy of Omega-3 Fatty Acid Therapy in Preventing Gastrointestinal Bleeding in Patients With CF-LVAD

NCT03784963

Phase 1/2 Terminated 35 enrolled University of Chicago
RandomizedParallel-groupOpen-labelPrevention

Summary

This study evaluates the efficacy of high-dose fish oil in decreasing rates of gastrointestinal bleeding in patients with continuous-flow left ventricular assist devices. Half of the patients without history of bleeding will receive fish oil while the other half will not. Half of the patients with history of bleeding will receive fish oil while the other half will not. Markers of angiogenesis and inflammation, as well as changes in the microbiome will be assessed in each group.

Timeline

Start
2019-01-23
Primary completion
2020-07-15
Completion
2020-07-15

Drugs

EvaluationDrugModalityDoseRoute
Subject Omega-3 fatty acids Unknown 4 g

Indications