Study of Brimonidine Tartrate Nanoemulsion Eye Drop Solution in the Treatment of Dry Eye Disease (DED)

Summary

This study evaluates the use of Brimonidine tartrate nanoemulsion eye drop solution in the treatment of Dry Eye Disease (DED). Half of participants will receive Brimonidine and half will receive ophthalmic buffered saline (placebo).

Timeline

Start

2018-12-03

Primary completion

2019-02-25

Completion

2019-02-25

Outcome

Missed primary endpoint

registry analysis (superiority test); OCU-310 vs Placebo; p = 0.739; Least squares mean difference -0.844 (95% CI -5.823 to 4.134) NCT03785340 ↗

Drugs

Indications