drugset / Trial / NCT03785574
Study of Different Therapeutic Strategies in Hydatidiform Mole With Lung Nodule
Recruiting
30 enrolled
Women's Hospital School Of Medicine Zhejiang University
First Affiliated Hospital of Wenzhou Medical University · collabHangzhou Fuyang Women And Children Hospital · collabHuzhou Maternity and Child Health Care Hospital · collabQilu Hospital of Shandong University · collabShaoxing Shangyu Women And Children Hospital · collabThe First People's Hospital of Yunnan · collabTianjin Central Hospital of Gynecology Obstetrics · collabTongji Hospital Affiliated to Tongji Medical College of HUST · collabWomen and Children's Hospital of Ningbo University · collabZhejiang Provincial Tongde Hospital · collab
RandomizedParallel-groupOpen-labelTreatment
Summary
The purpose of present study is to provide clinical evidences for the appropriate management of molar pregnancy with lung nodule. The hydatidiform mole patients with lung nodule ≥1.0cm will be randomized into 2 groups: A. treated with chemotherapy immediately, B. follow up until hCG level met FIGO diagnostic criteria of GTN (B1) or hCG level declined to normal spontaneously (B2). Lung nodule \<1.0cm will directly treated as group C
Timeline
- Start
- 2018-12-24
- Primary completion
- 2030-09-01
- Completion
- 2030-09-01
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | ACTD | Unknown | — | — |
| Subject | Methotrexate | Small molecule | — | — |