drugset / Trial / NCT03786887
The 90% Effective Dose of Nalbuphine in Mechanical Ventilated Patients in the ICU
SequentialOpen-labelTreatment
Summary
The aim of this study is to determine the effective nalbuphine dose in 90% of intubated patients in the ICU, including the continuous infusion dose and a bolus dose during moving to the lateral decubitus position. Pain will assessed using a Behavioural Pain Scale (BPS) requiring a score of 3-4.
Timeline
- Start
- 2018-10-24
- Primary completion
- 2019-10
- Completion
- 2019-10
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Nalbuphine | Small molecule | 0 mg/kg | — |
| Subject | Nalbuphine | Small molecule | 100 ug/kg | — |
Indications
No indication recorded.