drugset / Trial / NCT03789006

Antithymocyte Globulin and Azathioprine Versus Basiliximab and Mycophenolate Mofetil in Living Donor Kidney Transplantation

NCT03789006

RandomizedParallel-groupOpen-labelPrevention

Summary

Kidney transplantation is the best available treatment option for patients with end stage renal disease. However, kidney transplantation requires life-long use of immunosuppressive medication. Because of the high cost of these medications we need to carefully evaluate the cost-effectiveness of each drug regimen, especially in low-middle income countries. The objective of this clinical trial is to compare the efficiency and cost of two immunosuppressive protocols after living donor kidney transplantation: (1) antithymocyte globulin, tacrolimus, azathioprine and prednisolone versus (2) basiliximab, tacrolimus, mycophenolate mofetil and prednisolone.

Timeline

Start
2018-03-21
Primary completion
2022-03-21
Completion
2024-03-21

Drugs

EvaluationDrugModalityDoseRoute
Comparator Basiliximab Monoclonal antibody
Comparator Thymoglobulin Protein / enzyme biologic

Indications