drugset / Trial / NCT03799900
Assessment of Abuse Potential of Rapastinel in Humans
RandomizedCrossoverDouble-blindOther
Summary
Based on the pharmacological class of rapastinel, this study will be conducted to evaluate the abuse potential of single doses of rapastinel as compared with ketamine, a NMDAR antagonist that is a Schedule III dissociative anesthetic, and placebo in recreational polydrug users.
Timeline
- Start
- 2018-11-01
- Primary completion
- 2019-03-24
- Completion
- 2019-03-29
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Ketamine | Small molecule | — | Intravenous |
| Subject | Rapastinel | Other / unclassified | — | Intravenous |