drugset / Trial / NCT03799900

Assessment of Abuse Potential of Rapastinel in Humans

NCT03799900

Phase 1 Completed 72 enrolled Naurex, Inc
RandomizedCrossoverDouble-blindOther

Summary

Based on the pharmacological class of rapastinel, this study will be conducted to evaluate the abuse potential of single doses of rapastinel as compared with ketamine, a NMDAR antagonist that is a Schedule III dissociative anesthetic, and placebo in recreational polydrug users.

Timeline

Start
2018-11-01
Primary completion
2019-03-24
Completion
2019-03-29

Drugs

EvaluationDrugModalityDoseRoute
Subject Ketamine Small molecule Intravenous
Subject Rapastinel Other / unclassified Intravenous

Indications