Human Beta-2 Adrenergic Stimulation and Muscle Glucose Uptake

Phase 2 Completed 11 enrolled Maastricht University

RandomizedCrossoverDouble-blindTreatment

Summary

The purpose of this study is to investigate the effect of two weeks clenbuterol/placebo supplementation on skeletal muscle glucose disposal in healthy male volunteers.

Timeline

Start: 2019-06-01
Primary completion: 2021-04-23
Completion: 2021-04-23

Publications

van Beek SMM, Bruls YMH, Vanweert F, Fealy CE, Connell NJ, Schaart G, Moonen-Kornips E, Jorgensen JA, Vaz FM, Smeets ETHC, Joris PJ, Gemmink A, Houtkooper RH, Hesselink MKC, Bengtsson T, Havekes B, Schrauwen P, Hoeks J. Effect of beta2-agonist treatment on insulin-stimulated peripheral glucose disposal in healthy men in a randomised placebo-controlled trial. Nat Commun. 2023 Jan 12;14(1):173. doi: 10.1038/s41467-023-35798-5.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Clenbuterol	Small molecule	40 ug	Oral

Indications

No indication recorded.