drugset / Trial / NCT03801746
Drug-Drug Interaction Study of Vadadustat With Cyclosporine, Probenecid and Rifampin
RandomizedSequentialOpen-labelBasic science
Summary
This is a Phase 1, two-part, open-label study to evaluate the interaction of cyclosporine, probenecid, and rifampin as perpetrators with vadadustat (victim) in healthy male and female subjects.
Timeline
- Start
- 2018-07-20
- Primary completion
- 2018-08-15
- Completion
- 2018-08-15
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Cyclosporine | Peptide | 500 mg | Oral |
| Subject | Probenecid | Small molecule | 500 mg | Oral |
| Subject | Rifampin | Small molecule | 600 mg | Intravenous |
| Subject | Vadadustat | Small molecule | 300 mg | Oral |
Indications
No indication recorded.