drugset / Trial / NCT03801759
Drug-Drug Interaction Study of Vadadustat With Digoxin, Adefovir and Furosemide
Non-randomizedSequentialOpen-labelBasic science
Summary
This is a Phase 1, open-label, 3-arm, fixed sequence, study to evaluate vadadustat as a perpetrator of drug-drug interactions (DDIs) with digoxin, adefovir and furosemide in healthy male and female subjects.
Timeline
- Start
- 2018-07-20
- Primary completion
- 2018-09-30
- Completion
- 2018-09-30
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Adefovir | Unknown | 10 mg | Oral |
| Subject | Digoxin | Other / unclassified | 0.5 mg | Oral |
| Subject | Furosemide | Other / unclassified | 40 mg | Oral |
| Subject | Vadadustat | Small molecule | 600 mg | Oral |
Indications
No indication recorded.