drugset / Trial / NCT03802747

Immunotherapy Combined With Y-90 and SBRT for Colorectal Liver Metastases

NCT03802747

Non-randomizedSingle-groupOpen-labelTreatment

Summary

This study is evaluating the combination of Y-90 radioembolization followed by SBRT with the immunotherapy drugs, durvalumab and tremelimumab, to improve disease control of liver metastases for patients with microsatellite stable colorectal cancer.

Timeline

Start
2019-08
Primary completion
2023-12
Completion
2024-12

Drugs

EvaluationDrugModalityDoseRoute
Subject Durvalumab Monoclonal antibody 1500 mg
Subject Tremelimumab Monoclonal antibody 75 mg

Indications